| Plant Molecular Biology |
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| Group Leader |
Dr. Rakesh Tuli, Director, NBRI |
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Contact |
Work
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91-522-2205849, 2205698 |
| Home |
91-522-2789499, 2789535 |
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Other Scientists of the Group
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Dr. Samir Vishwanath Sawant , Scientist 'E I'
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Group works on
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The group possesses knowledge base and technical
expertise in the area of plant molecular biology and genetic engineering
of crop plants for basic research and industrial applications. The
group has advanced expertise in the designing and chemical synthesis
of genes and plant expression systems. Present activities aim at
the development of genetically engineered plants for agronomically
improved transgenic cultivars, edible vaccines, industrially valuable
proteins and basic studies on gene expression, metabolic engineering,
plant development, environment responses and phytodiversity.
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Objectives
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- Development of transgenic plants improved for agronomically
important characters.
- Characterization and designing of genes for protection of
plants against insect pests.
- Expression of industrially valuable target proteins in bacteria
and plants.
- Consultation and contract research for biotechnology industry.
- Characterisation and improvement of germ plasm of medicinal
plants.
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Achievements
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National
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- Technology for designing, chemical synthesis and assembly
of genes.
- Designing and licensing of novel δ -endotoxin coding
genes and the development of transgenic cotton and tobacco lines
for complete control of bollworms Spodoptera litura
and Helicoverpa armigera
- Development of transgenic plants immunoprotective against
rabies.
- Genetic transformation of Coker cotton and groundnut.
- Designing of a variety of bidirectional and high expression
artificial promoter cassettes for constitutive or regulated
gene expression in plants.
- Providing consultation to biotechnology industry.
- Characterisation of germplasm of Ashwagandha (Withania
Somnifera)
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International
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- Designing of novel δ-endotoxin-coding genes to achieve
complete morality of Spodoptera litura in all stages
of larval development.
- Development of novel plant gene expression modules, bidirectional
promoters and two component regulated promoters for gene expression
in transgenic plants, specially F1 hybrids.
- Development of protocols for efficient genetic transformation
and regeneration in cotton.
- Technology for the expression of immunoprotective rabies
capsid protein in plants.
- Development of vectors for nuclear as well as chloroplast
transformation in plants.
- Patents related to plant transformation, δ -endotoxin
genes and plant promoters.
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Feedback required
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National Level
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- National and industrial needs in the area of transgenic cultivars
for resistance to insect pests, drought tolerance and other
agronomically relevant characters. Insect resistant transgenic
varieties of cotton, castor, groundnut and pigeon pea are available
(or are in progress) for licensing.
- Collaborations for introducing insect pest toxic genes in
crop plants.
- Needs of industry to develop and synthesize recombinant,
industrially or pharmaceutically important proteins.
- Industrial needs in the area of edible and DNA vaccines,
diagnostic probes, cloning and synthesis of genes and novel
proteins.
- Innovative contract R & D in molecular biology.
- DNA fingerprinting and chemotyping of medicinally important
plants.
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International Level
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- Needs in the area of developing transgenic cultivars for
resistance to insect pests and other agronomically relevant
characters.
- Industrial needs to employ transgenic plants in commercial
synthesis of recombinant proteins, through nuclear or chloroplast
transformation.
- Industrial needs in the area of edible and DNA vaccines,
diagnostic probes, cloning and synthesis of genes and novel
proteins.
- Highly expressing and / or tightly regulated promoters suitable
for F1 hybrids.
- Contract R & D in related innovative areas.
- Collaborations in the area of gene regulation, chromatin
modelling and stress tolerance in plants.
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